Description

2-Ethyl-6-Methylisonicotinonitrile is a specialized pyridine derivative nitrile compound, serving as a critical building block in advanced organic synthesis. Its value lies in its functionalized structure, which provides a versatile scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This intermediate is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used as a precursor in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or photoactive compounds.
• Custom Synthesis and Contract Manufacturing: A vital component for custom chemical synthesis houses serving the life sciences sector.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for biochemical and diagnostic applications.

Basic Information

Product Name	2-Ethyl-6-Methylisonicotinonitrile
CAS No.	945463-94-5
Molecular Formula	C9H10N2
Molecular Weight	146.19 g/mol
Synonyms	6-Methyl-2-ethylisonicotinonitrile; 2-Ethyl-6-methylpyridine-4-carbonitrile; 4-Cyano-2-ethyl-6-methylpyridine; 2-Ethyl-6-methyl-4-pyridinecarbonitrile; Isonicotinonitrile, 2-ethyl-6-methyl-; 2-Ethyl-6-methyl-4-cyanopyridine
EINECS	Contact for details

Quality Control

Our 2-Ethyl-6-Methylisonicotinonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.