Description

2-[4-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Oxazole is a high-value, synthetically versatile organoboron building block. This compound matters as a critical intermediate in modern cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for applications in drug discovery, agrochemical synthesis, and advanced material science.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides, herbicides, and fungicides requiring specific aryl-oxazole motifs.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes.
• Academic & Industrial R&D: A fundamental reagent for synthetic organic chemistry research in both university and corporate laboratory settings.

Basic Information

Product Name	2-[4-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Oxazole
CAS No.	945226-59-5
Molecular Formula	C16H22BNO3
Molecular Weight	287.17 g/mol
Synonyms	2-(4-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)oxazole; 2-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-methylphenyl]oxazole; 4-Methyl-3-(oxazol-2-yl)phenylboronic acid pinacol ester; (3-(Oxazol-2-yl)-4-methylphenyl)boronic acid pinacol ester; 945226-59-5; Boronic acid, B-[3-(2-oxazolyl)-4-methylphenyl]-, 1,1-dimethylethyl ester; B-[3-(Oxazol-2-yl)-4-methylphenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-[4-Methyl-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Oxazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.