Description

1H-Pyrrolo[3,2-B]Pyridine-6-Carbonitrile is a high-purity nitrogen-containing heterocyclic building block of significant interest in advanced organic synthesis. Its unique fused bicyclic structure and nitrile functional group make it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Serves as a building block for organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.
• Academic & Contract Research: Utilized in universities and CROs for methodological studies and the exploration of new chemical spaces.
• Custom Synthesis: A starting point for the contract manufacturing of complex, proprietary molecules for client-specific projects.

Basic Information

Product Name	1H-Pyrrolo[3,2-B]Pyridine-6-Carbonitrile
CAS No.	944937-79-5
Molecular Formula	C8H5N3
Molecular Weight	143.15 g/mol
Synonyms	6-Cyano-1H-pyrrolo[3,2-b]pyridine; 1H-Pyrrolo[3,2-b]pyridine-6-carbonitrile; 6-CN-1H-pyrrolo[3,2-b]pyridine; Pyrrolo[3,2-b]pyridine-6-carbonitrile; 6-Cyanopyrrolo[3,2-b]pyridine; 1H-Pyrrolo[3,2-b]pyridine-6-carbonitrile; 6-Cyano-7-azaindole (common name); 6-Cyano-1H-7-azaindole
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[3,2-B]Pyridine-6-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high standards, from early-stage research to pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.