Description

1-(1H-Pyrrolo[2,3-B]Pyridin-5-Yl)-Ethanone is a high-purity organic building block and pharmaceutical intermediate of significant interest in modern synthetic chemistry. This compound matters for its role as a versatile precursor in the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research. Pharmaceutical R&D teams and fine chemical manufacturers need this material for constructing complex heterocyclic scaffolds. Its defined structure enables precise molecular modifications critical for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of kinase inhibitors and other targeted therapeutics.
• Organic Synthesis Research: Used in academic and industrial laboratories for constructing complex pyrrolopyridine-based molecular architectures.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel crop protection agents.
• Material Science: Investigated for the development of organic electronic materials and ligands for catalytic systems.
• Bioconjugation Chemistry: Potential use in creating labeled compounds or probes for biochemical studies.

Basic Information

Product Name	1-(1H-Pyrrolo[2,3-B]Pyridin-5-Yl)-Ethanone
CAS No.	944937-14-8
Molecular Formula	C9H8N2O
Molecular Weight	160.17 g/mol
Synonyms	5-Acetyl-1H-pyrrolo[2,3-b]pyridine; 1-(1H-Pyrrolo[2,3-b]pyridin-5-yl)ethanone; 5-Acetylpyrrolo[2,3-b]pyridine; Ethanone, 1-(1H-pyrrolo[2,3-b]pyridin-5-yl)-; 1-(1H-Pyrrolo[2,3-b]pyridin-5-yl)ethan-1-one
EINECS	Contact for details

Quality Control

Our 1-(1H-Pyrrolo[2,3-B]Pyridin-5-Yl)-Ethanone is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.