Description

2-Bromo-3-(Chloromethyl)Pyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional reactivity, featuring both bromine and chloromethyl groups, makes it an invaluable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Synthesis: Used to create advanced pyridine-based herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science: Building block for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A high-value intermediate for custom synthesis projects and scale-up services under cGMP conditions.

Basic Information

Product Name	2-Bromo-3-(Chloromethyl)Pyridine
CAS No.	944906-87-0
Molecular Formula	C6H5BrClN
Molecular Weight	206.47 g/mol
Synonyms	3-(Chloromethyl)-2-bromopyridine; 2-Bromo-3-(chloromethyl)pyridine; 2-Bromo-3-pyridinylmethyl chloride; (2-Bromo-3-pyridyl)methyl chloride; Pyridine, 2-bromo-3-(chloromethyl)-; 944906-87-0; 2-Bromo-3-chloromethylpyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-(Chloromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment supports applications requiring high-purity intermediates, from research to pilot and commercial-scale production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.