Description

1-(2-Chloro-5-(Trifluoromethyl)Pyridin-3-Yl)Ethanone is a high-value trifluoromethylpyridine derivative, a crucial building block in advanced organic synthesis. Its molecular structure, featuring both a chloro and a trifluoromethyl group on the pyridine ring, makes it an essential intermediate for creating compounds with enhanced biological activity and physicochemical properties. This product is primarily targeted at pharmaceutical R&D and agrochemical manufacturers developing next-generation active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the manufacture of advanced pesticides, herbicides, and fungicides, where the trifluoromethyl group improves lipophilicity and metabolic stability.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in the development of specialty polymers and advanced materials.
• Chemical Research & Development: Employed in academic and industrial labs for method development and exploring new reaction pathways in fluoroorganic chemistry.
• Liquid Crystal & OLED Materials: A potential intermediate for electronic chemicals used in display technologies due to its aromatic and halogenated structure.

Basic Information

Product Name	1-(2-Chloro-5-(Trifluoromethyl)Pyridin-3-Yl)Ethanone
CAS No.	944904-73-8
Molecular Formula	C8H5ClF3NO
Molecular Weight	223.58 g/mol
Synonyms	2-Chloro-5-(trifluoromethyl)-3-acetylpyridine; 3-Acetyl-2-chloro-5-(trifluoromethyl)pyridine; 1-[2-Chloro-5-(trifluoromethyl)-3-pyridinyl]ethanone; Ethanone, 1-[2-chloro-5-(trifluoromethyl)-3-pyridinyl]-; 2-Chloro-3-acetyl-5-trifluoromethylpyridine; 1-(2-Chloro-5-(trifluoromethyl)pyridin-3-yl)ethan-1-one
EINECS	Contact for details

Quality Control

Our 1-(2-Chloro-5-(Trifluoromethyl)Pyridin-3-Yl)Ethanone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards and can support regulatory documentation needs for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.