Description

2-Methoxy-5-(Trifluoromethyl)Nicotinic Acid is a high-purity, multi-functional chemical building block prized for its unique trifluoromethyl and methoxy-substituted pyridine core. This compound is essential for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its structure imparts desirable metabolic stability and bioavailability. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Methoxy-5-(Trifluoromethyl)Nicotinic Acid
CAS No.	944904-62-5
Molecular Formula	C8H6F3NO3
Molecular Weight	221.13 g/mol
Synonyms	5-(Trifluoromethyl)-2-methoxynicotinic acid; 2-Methoxy-5-(trifluoromethyl)pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 2-methoxy-5-(trifluoromethyl)-; 2-Methoxy-5-trifluoromethylnicotinic acid; 944904-62-5; 2-Methoxy-5-(trifluoromethyl)-3-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Methoxy-5-(Trifluoromethyl)Nicotinic Acid is manufactured under a strict quality management system. Our products undergo rigorous quality testing, including HPLC for purity and identity confirmation, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.