Description

2-Methoxy-6-(Trifluoromethyl)Nicotinaldehyde is a versatile and high-value nicotinaldehyde derivative, distinguished by its methoxy and trifluoromethyl substituents. This compound serves as a critical advanced pharmaceutical intermediate and a valuable building block in modern synthetic chemistry. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides, leveraging the biological activity of the pyridine core and trifluoromethyl group.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Intermediate for creating functional organic molecules used in electronic materials, liquid crystals, or organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Serves as a starting point for synthesizing molecular probes and tools used in biochemical and pharmacological research.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	2-Methoxy-6-(Trifluoromethyl)Nicotinaldehyde
CAS No.	944904-45-4
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	6-(Trifluoromethyl)-2-methoxynicotinaldehyde; 2-Methoxy-6-(trifluoromethyl)pyridine-3-carbaldehyde; 3-Formyl-2-methoxy-6-(trifluoromethyl)pyridine; 2-Methoxy-6-trifluoromethylnicotinaldehyde; 2-Methoxy-6-trifluoromethyl-3-pyridinecarboxaldehyde; 3-Pyridinecarboxaldehyde, 2-methoxy-6-(trifluoromethyl)-; 944904-45-4
EINECS	Contact for details

Quality Control

Our 2-Methoxy-6-(Trifluoromethyl)Nicotinaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, assay, and impurity profiles. Our quality management system is designed to meet the stringent requirements of GMP (Good Manufacturing Practice) for advanced intermediates, supporting our clients' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.