Description

7-(Trifluoromethyl)-2,3-Dihydro-1H-Pyrido[2,3-B][1,4]Oxazine is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core structure, featuring a fused pyrido-oxazine ring system and a strategically positioned trifluoromethyl group, makes it a critical intermediate for developing novel bioactive molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of new active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: Serves as a key scaffold in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets, oncology, and anti-infective therapies.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve metabolic stability and bioavailability.
• Material Science Precursor: Acts as a building block for specialty chemicals and advanced materials, including liquid crystals and organic electronic components.
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a fragment in fragment-based drug discovery (FBDD).
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	7-(Trifluoromethyl)-2,3-Dihydro-1H-Pyrido[2,3-B][1,4]Oxazine
CAS No.	944900-45-2
Molecular Formula	C8H7F3N2O
Molecular Weight	204.15 g/mol
Synonyms	7-(Trifluoromethyl)-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazine; 2,3-Dihydro-7-(trifluoromethyl)-1H-pyrido[2,3-b][1,4]oxazine; 1H-Pyrido[2,3-b][1,4]oxazine, 2,3-dihydro-7-(trifluoromethyl)-; 7-Trifluoromethyl-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazine; CAS 944900-45-2
EINECS	Contact for details

Quality Control

Our 7-(Trifluoromethyl)-2,3-Dihydro-1H-Pyrido[2,3-B][1,4]Oxazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support our partners with full traceability and data packages suitable for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.