Description

2-Methoxy-5-(Trifluoromethyl)Pyridin-3-Amine is a high-value pyridine derivative and a versatile chemical building block prized for its unique trifluoromethyl and methoxy substituents. This compound is essential for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its structural motifs confer desirable biological activity and metabolic stability. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for enhanced efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or emissive materials for OLEDs.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up campaigns in fine chemical production.
• Life Science Research: Used as a biochemical tool and probe in medicinal chemistry for structure-activity relationship (SAR) studies.

Basic Information

Product Name	2-Methoxy-5-(Trifluoromethyl)Pyridin-3-Amine
CAS No.	944900-42-9
Molecular Formula	C7H7F3N2O
Molecular Weight	192.14 g/mol
Synonyms	3-Amino-2-methoxy-5-(trifluoromethyl)pyridine; 2-Methoxy-5-(trifluoromethyl)-3-pyridinamine; 5-(Trifluoromethyl)-2-methoxypyridin-3-amine; 3-Pyridinamine, 2-methoxy-5-(trifluoromethyl)-; 2-Methoxy-5-trifluoromethylpyridin-3-ylamine
EINECS	Contact for details

Quality Control

Our 2-Methoxy-5-(Trifluoromethyl)Pyridin-3-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.