Description

2-Amino-5-(Trifluoromethyl)Nicotinic Acid is a high-value trifluoromethylated pyridine derivative, serving as a critical building block in modern synthetic chemistry. Its unique structure, combining a nicotinic acid core with amino and trifluoromethyl substituents, makes it indispensable for creating novel compounds with enhanced biological activity and physicochemical properties. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of advanced active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in areas such as kinase inhibitors, antiviral agents, and anti-inflammatory compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve metabolic stability and bioavailability.
• Material Science Research: Employed in the synthesis of specialized ligands, metal-organic frameworks (MOFs), and functional polymers.
• Chemical Biology & Proteomics: Serves as a building block for creating chemical probes and affinity tags to study biological systems.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Amino-5-(Trifluoromethyl)Nicotinic Acid
CAS No.	944900-39-4
Molecular Formula	C7H5F3N2O2
Molecular Weight	206.12 g/mol
Synonyms	5-(Trifluoromethyl)-2-aminonicotinic Acid; 2-Amino-5-(trifluoromethyl)pyridine-3-carboxylic Acid; 3-Carboxy-5-(trifluoromethyl)-2-aminopyridine; 2-Amino-3-carboxy-5-(trifluoromethyl)pyridine; 2-Amino-5-trifluoromethylnicotinic Acid; 5-Trifluoromethyl-2-aminonicotinic Acid; 2-Amino-5-(trifluoromethyl)-3-pyridinecarboxylic Acid
EINECS	Contact for details

Quality Control

Our 2-Amino-5-(Trifluoromethyl)Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.