Description

5-Amino-2-Trifluoromethyl-Pyridine-4-Carbaldehyde is a high-value, multi-functional pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and aldehyde functional groups make it an indispensable intermediate for creating novel compounds with enhanced biological activity and material properties. This chemical is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the trifluoromethyl group can improve metabolic stability and lipophilicity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functional polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing characteristics.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme inhibition.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-Amino-2-Trifluoromethyl-Pyridine-4-Carbaldehyde
CAS No.	944900-36-1
Molecular Formula	C7H5F3N2O
Molecular Weight	190.12 g/mol
Synonyms	4-Pyridinecarboxaldehyde, 5-amino-2-(trifluoromethyl)-; 5-Amino-2-(trifluoromethyl)isonicotinaldehyde; 5-Amino-2-(trifluoromethyl)pyridine-4-carboxaldehyde; 2-(Trifluoromethyl)-5-amino-4-pyridinecarboxaldehyde; 5-Amino-2-trifluoromethyl-4-pyridinecarbaldehyde; 4-Formyl-5-amino-2-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

Every batch of 5-Amino-2-Trifluoromethyl-Pyridine-4-Carbaldehyde is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.