Description

3-Bromo-5-(1-Pyrrolidinyl)-Pyridine is a versatile heterocyclic building block featuring a bromine substituent and a pyrrolidine ring, offering two distinct reactive handles for further chemical elaboration. This compound is of significant value in medicinal chemistry and materials science for constructing complex molecular architectures. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries for use as a key intermediate in the synthesis of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides that require specific heterocyclic scaffolds.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated ligands used in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, conductive polymers, and other functional organic materials.
• Chemical Biology Probes: Useful for creating tagged molecules and probes to study biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	3-Bromo-5-(1-Pyrrolidinyl)-Pyridine
CAS No.	944718-19-8
Molecular Formula	C9H11BrN2
Molecular Weight	227.10 g/mol
Synonyms	3-Bromo-5-(pyrrolidin-1-yl)pyridine; 5-(1-Pyrrolidinyl)-3-bromopyridine; 3-Bromo-5-pyrrolidin-1-ylpyridine; Pyridine, 3-bromo-5-(1-pyrrolidinyl)-; 944718-19-8; 3-Bromo-5-pyrrolidinopyridine
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-(1-Pyrrolidinyl)-Pyridine is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Assay (Titration)	≥96.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.