Description

5-Bromo-2-(Piperazin-1-Yl)-4-Methylpyridine is a high-value, heterocyclic organic building block featuring a pyridine core substituted with bromine and a piperazine moiety. This compound is critical for medicinal chemistry research and development, serving as a versatile intermediate in the synthesis of novel pharmaceutical candidates. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific pharmacophores into target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its modifiable bromine and piperazine functional groups.
• Agrochemical Synthesis: Intermediate in the development of new active ingredients for crop protection products.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes to study biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic Research: Used in university and institutional labs for advanced organic synthesis and methodological development.

Basic Information

Product Name	5-Bromo-2-(Piperazin-1-Yl)-4-Methylpyridine
CAS No.	944582-93-8
Molecular Formula	C10H14BrN3
Molecular Weight	256.14 g/mol
Synonyms	4-Methyl-5-bromo-2-(piperazin-1-yl)pyridine; 5-Bromo-4-methyl-2-piperazin-1-ylpyridine; 2-(1-Piperazinyl)-5-bromo-4-methylpyridine; 5-Bromo-2-(1-piperazinyl)-4-methylpyridine; 5-Bromo-4-methyl-2-(piperazin-1-yl)pyridine; 944582-93-8; 5-Bromo-2-piperazin-1-yl-4-methylpyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(Piperazin-1-Yl)-4-Methylpyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of pharmaceutical R&D and advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This compound may be light-sensitive and hygroscopic; therefore, handling under an inert atmosphere and desiccated conditions is recommended for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Purity (HPLC Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.