Description

2-(4-Iodo-Phenyl)-8-Trifluoromethyl-Imidazo[1,2-A]Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure incorporating iodine and trifluoromethyl functional groups. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, especially within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Key building block in the research and synthesis of novel drug candidates, particularly for targeted therapies.
• Critical intermediate for the development of imidazo[1,2-a]pyridine-based compounds with potential pharmacological activity.
• Used in medicinal chemistry for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Employed in the discovery of potential treatments for cancer, leveraging its halogenated and fluorinated motifs.
• Applicable in the development of diagnostic agents or imaging probes due to the presence of the iodine atom.
• Serves as a versatile scaffold in academic and industrial research for exploring new chemical entities (NCEs).

Basic Information

Product Name	2-(4-Iodo-Phenyl)-8-Trifluoromethyl-Imidazo[1,2-A]Pyridine
CAS No.	944581-03-7
Molecular Formula	C14H8F3IN2
Molecular Weight	388.13 g/mol
Synonyms	2-(4-Iodophenyl)-8-(trifluoromethyl)imidazo[1,2-a]pyridine; 8-Trifluoromethyl-2-(4-iodophenyl)imidazo[1,2-a]pyridine; 2-(4-Iodo-phenyl)-8-trifluoromethyl-imidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 2-(4-iodophenyl)-8-(trifluoromethyl)-; 944581-03-7; AI3-63562; ZINC000103079553
EINECS	Contact for details

Quality Control

Our 2-(4-Iodo-Phenyl)-8-Trifluoromethyl-Imidazo[1,2-A]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.