Description

2-(4-Iodo-Phenyl)-7-Trifluoromethyl-Imidazo[1,2-A]Pyridine is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring an imidazopyridine core with iodine and trifluoromethyl substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research and development teams in the pharmaceutical and agrochemical sectors, where it serves as a key precursor in medicinal chemistry programs and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a versatile scaffold in the research and synthesis of new drug candidates, particularly in oncology, CNS disorders, and anti-infective therapies.
• Agrochemical Research: Used as a building block for developing novel pesticides, herbicides, and fungicides, leveraging the bioactivity of the imidazopyridine moiety.
• Material Science Precursor: Employed in the synthesis of advanced organic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient character.
• Chemical Biology Probe: Acts as a core structure for creating molecular probes and tags used in biochemical assays and diagnostic research.
• Cross-Coupling Reactions: The aryl iodide group makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create diverse biaryl structures.
• Fluorinated Compound Library Synthesis: The trifluoromethyl group is prized in medicinal chemistry for its ability to modulate lipophilicity, metabolic stability, and bioavailability, making this compound valuable for focused library synthesis.

Basic Information

Product Name	2-(4-Iodo-Phenyl)-7-Trifluoromethyl-Imidazo[1,2-A]Pyridine
CAS No.	944580-94-3
Molecular Formula	C14H8F3IN2
Molecular Weight	388.13 g/mol
Synonyms	2-(4-Iodophenyl)-7-(trifluoromethyl)imidazo[1,2-a]pyridine; 7-(Trifluoromethyl)-2-(4-iodophenyl)imidazo[1,2-a]pyridine; 2-(4-Iodo-phenyl)-7-trifluoromethyl-imidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 2-(4-iodophenyl)-7-(trifluoromethyl)-; 944580-94-3
EINECS	Contact for details

Quality Control

Our 2-(4-Iodo-Phenyl)-7-Trifluoromethyl-Imidazo[1,2-A]Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.