Description

2-(4-Iodo-Phenyl)-5-Trifluoromethyl-Imidazo[1,2-A]Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure incorporating iodine and trifluoromethyl functional groups. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel drug candidates with potential for enhanced biological activity and metabolic stability. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and pharmacokinetic properties of lead compounds.
• API Development: Serves as a precursor in the development and scale-up of Active Pharmaceutical Ingredients (APIs) for preclinical and clinical trials.
• Chemical Biology Probes: Employed in the design of molecular probes for studying biological pathways and target validation due to its distinctive structural motifs.
• Agrochemical Research: Potential application as an intermediate in the development of new agrochemicals, such as herbicides or fungicides.
• Material Science: Investigated for use in the synthesis of organic electronic materials or metal-organic frameworks (MOFs) due to its aromatic and halogenated structure.

Basic Information

Product Name	2-(4-Iodo-Phenyl)-5-Trifluoromethyl-Imidazo[1,2-A]Pyridine
CAS No.	944580-84-1
Molecular Formula	C14H8F3IN2
Molecular Weight	388.13 g/mol
Synonyms	2-(4-Iodophenyl)-5-(trifluoromethyl)imidazo[1,2-a]pyridine; 5-(Trifluoromethyl)-2-(4-iodophenyl)imidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 2-(4-iodophenyl)-5-(trifluoromethyl)-; 2-(p-Iodophenyl)-5-trifluoromethylimidazo[1,2-a]pyridine; 944580-84-1; 2-(4-Iodo-Phenyl)-5-Trifluoromethyl-Imidazo[1,2-A]Pyridine; 5-Trifluoromethyl-2-(4-iodophenyl)imidazo[1,2-a]pyridine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for advanced pharmaceutical intermediates. Each batch is analyzed using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) are available upon request, providing detailed batch-specific data. We adhere to a quality management system and can support development projects requiring GMP-grade material upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.