Description

[2-(3-Bromo-Phenyl)-Ethyl]-(4-Trifluoromethyl-Pyridin-2-Yl)-Amine is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold combining bromophenyl, ethylamine, and trifluoromethylpyridine moieties. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate its distinct halogenated and fluorinated structure into new molecular entities.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its bromine and trifluoromethyl functional groups.
• Agrochemical Development: Acts as a precursor in the research and synthesis of novel herbicides, fungicides, and insecticides.
• Chemical Biology Probes: Employed in the development of molecular probes and tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis organizations (CSOs) and CDMOs producing bespoke compounds for client projects.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	[2-(3-Bromo-Phenyl)-Ethyl]-(4-Trifluoromethyl-Pyridin-2-Yl)-Amine
CAS No.	944580-78-3
Molecular Formula	C14H12BrF3N2
Molecular Weight	345.16 g/mol
Synonyms	N-[2-(3-Bromophenyl)ethyl]-4-(trifluoromethyl)pyridin-2-amine; 2-[[2-(3-Bromophenyl)ethyl]amino]-4-(trifluoromethyl)pyridine; 4-Trifluoromethyl-2-[[2-(3-bromophenyl)ethyl]amino]pyridine; 2-((2-(3-Bromophenyl)ethyl)amino)-4-(trifluoromethyl)pyridine; (4-Trifluoromethyl-pyridin-2-yl)-[2-(3-bromo-phenyl)-ethyl]-amine
EINECS	Contact for details

Quality Control

Our [2-(3-Bromo-Phenyl)-Ethyl]-(4-Trifluoromethyl-Pyridin-2-Yl)-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our commitment to quality supports your research and development needs with reliable, high-purity materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.