Description

Pentafluorophenyl Isoquinoline-4-Carboxylate is a high-value, specialized fluorinated building block used in advanced organic synthesis. This compound is critical for researchers and manufacturers developing novel pharmaceuticals and agrochemicals, where its unique pentafluorophenyl ester group enables efficient coupling reactions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides with enhanced activity and environmental profiles.
• Ligand and Catalyst Synthesis: Serves as a building block for creating sophisticated ligands used in asymmetric catalysis and transition metal complexes.
• Material Science: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, due to its fluorinated aromatic system.
• Peptide & Protein Modification: Acts as an efficient acylating agent for modifying biomolecules under mild conditions.
• Chemical Biology Probes: Utilized to create fluorescent or affinity tags for studying biological processes and target identification.

Basic Information

Product Name	Pentafluorophenyl Isoquinoline-4-Carboxylate
CAS No.	944450-77-5
Molecular Formula	C₁₇H₆F₅NO₂
Molecular Weight	351.23 g/mol
Synonyms	4-Isoquinolinecarboxylic acid, 2,3,4,5,6-pentafluorophenyl ester; Pentafluorophenyl 4-isoquinolinecarboxylate; 4-(Pentafluorobenzoyloxy)isoquinoline; Isoquinoline-4-carboxylic acid pentafluorophenyl ester; PFP-Isoquinoline-4-COO-ester; CAS 944450-77-5
EINECS	Contact for details

Quality Control

Every batch of Pentafluorophenyl Isoquinoline-4-Carboxylate is manufactured under strict quality management systems. We guarantee high-purity material suitable for demanding research and scale-up applications. Our products undergo rigorous quality testing, including HPLC, NMR, and MS analysis, to ensure compliance with customer specifications and industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.