Description

6-[(1-Methylpiperidin-4-Yl)Oxy]Pyridin-3-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its unique piperidine-pyridine hybrid structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily utilized by pharmaceutical R&D laboratories, contract research/manufacturing organizations (CROs/CMOs), and fine chemical suppliers serving the global life sciences sector.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates targeting various disease pathways.
• CNS Drug Research: Used in the development of compounds for neurological and psychiatric disorders, leveraging its structural motifs common in receptor-targeted therapies.
• Oncology Research: Serves as a scaffold for creating novel kinase inhibitors and other targeted cancer therapeutics.
• Chemical Biology & Proteomics: Employed as a molecular probe or linker in the study of biological systems and protein interactions.
• Custom Synthesis & Scale-Up: Supplied to CROs and CMOs for process development, optimization, and commercial-scale GMP manufacturing.
• Academic Research: Used in university and institutional labs for medicinal chemistry programs and novel heterocyclic compound exploration.

Basic Information

Product Name	6-[(1-Methylpiperidin-4-Yl)Oxy]Pyridin-3-Amine
CAS No.	944401-79-0
Molecular Formula	C11H17N3O
Molecular Weight	207.27 g/mol
Synonyms	3-Amino-6-[(1-methyl-4-piperidinyl)oxy]pyridine; 6-[(1-Methyl-4-piperidinyl)oxy]-3-pyridinamine; 6-(1-Methylpiperidin-4-yloxy)pyridin-3-amine; 3-Pyridinamine, 6-[(1-methyl-4-piperidinyl)oxy]-; 944401-79-0; 6-(N-Methyl-4-piperidyloxy)-3-aminopyridine
EINECS	Contact for details

Quality Control

Every batch of 6-[(1-Methylpiperidin-4-Yl)Oxy]Pyridin-3-Amine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for pharmaceutical R&D and scale-up. A detailed Certificate of Analysis (COA) including HPLC purity, identity confirmation (NMR, IR, MS), and impurity profile is supplied with each shipment. Our quality commitment aligns with ICH guidelines and supports regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.