Description

2-Amino-5-Bromoisonicotinonitrile is a versatile and high-value brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both amino and nitrile functional groups adjacent to a bromine substituent, makes it an indispensable intermediate for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive pyridine core.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Functional Material Development: Employed in the research of organic semiconductors, liquid crystals, and photoactive compounds.
• Chemical Biology Probes: Utilized to build molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis Building Block: Provides a versatile handle for medicinal chemistry and parallel synthesis libraries.

Basic Information

Product Name	2-Amino-5-Bromoisonicotinonitrile
CAS No.	944401-72-3
Molecular Formula	C6H4BrN3
Molecular Weight	198.02 g/mol
Synonyms	5-Bromo-2-aminopyridine-4-carbonitrile; 5-Bromo-2-amino-4-cyanopyridine; 2-Amino-5-bromo-4-cyanopyridine; 4-Cyano-5-bromopyridin-2-amine; Isonicotinonitrile, 2-amino-5-bromo-; 5-Bromo-2-aminoisonicotinonitrile; 2-Amino-5-bromopyridine-4-carbonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-5-Bromoisonicotinonitrile is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.