Description

5-Bromo-4-Fluoropyridin-2-Amine is a high-purity, multi-functional heterocyclic building block essential for modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking to introduce halogenated pyridine motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule therapeutics where the bromo and fluoro substituents allow for further functionalization via cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating novel nitrogen-containing ligands for transition metal catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or organic light-emitting diodes (OLEDs).
• Chemical Biology Probe: Utilized as a scaffold for developing molecular probes and tags to study biological systems.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-Bromo-4-Fluoropyridin-2-Amine
CAS No.	944401-69-8
Molecular Formula	C5H4BrFN2
Molecular Weight	191.00 g/mol
Synonyms	2-Amino-5-bromo-4-fluoropyridine; 4-Fluoro-5-bromopyridin-2-amine; 5-Bromo-4-fluoro-2-pyridinamine; 5-Bromo-4-fluoropyridin-2-ylamine; 2-Pyridinamine, 5-bromo-4-fluoro-; 944401-69-8
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Fluoropyridin-2-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC, GC, NMR, and MS. We adhere to relevant industry standards and can support regulatory filings for pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.