Description

5-Bromo-6-Fluoropyridin-2-Amine is a high-purity, multi-functional halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which provides distinct reactivity for constructing complex heterocyclic scaffolds essential in modern chemical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced polymers, liquid crystals, and electronic materials.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for designing molecular probes, enzyme inhibitors, and bioconjugation reagents.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to introduce complex amine functionalities.
• Contract Research & Development (CRO/CMO): Supplied to research organizations for custom synthesis and library production for drug discovery campaigns.

Basic Information

Product Name	5-Bromo-6-Fluoropyridin-2-Amine
CAS No.	944401-65-4
Molecular Formula	C5H4BrFN2
Molecular Weight	191.00 g/mol
Synonyms	2-Amino-5-bromo-6-fluoropyridine; 5-Bromo-6-fluoro-2-pyridinamine; 6-Fluoro-5-bromopyridin-2-amine; 5-Bromo-6-fluoro-2-aminopyridine; 2-Pyridinamine, 5-bromo-6-fluoro-; 944401-65-4; 5-Br-6-F-2-AP
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-Fluoropyridin-2-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.