Description

2-Amino-5-Bromo-4-Trifluoromethylpyridine is a high-value, multi-functional pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring amino, bromo, and trifluoromethyl substituents, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating specialized ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its electron-deficient aromatic system.
• Chemical Biology Probes: Utilized as a core structure for developing molecular probes and tags to study biological processes and protein interactions.

Basic Information

Product Name	2-Amino-5-Bromo-4-Trifluoromethylpyridine
CAS No.	944401-56-3
Molecular Formula	C7H5BrF3N2
Molecular Weight	255.03 g/mol
Synonyms	5-Bromo-2-amino-4-(trifluoromethyl)pyridine; 4-Trifluoromethyl-2-amino-5-bromopyridine; 2-Pyridinamine, 5-bromo-4-(trifluoromethyl)-; 5-Bromo-4-trifluoromethylpyridin-2-amine; 2-Amino-5-bromo-4-(trifluoromethyl)pyridine; 5-Bromo-2-amino-4-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Bromo-4-Trifluoromethylpyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting purity, assay, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.