Description

4-(4-Methyl-Pyridin-2-Yloxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-value, protected piperidine derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a versatile, nitrogen-containing scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in the synthesis of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis: Serves as a versatile precursor for introducing functionalized piperidine motifs into more complex molecular architectures.
• Agrochemical Research: Potential intermediate in the development of novel crop protection agents and pesticides.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for methodological development and novel compound library synthesis.

Basic Information

Product Name	4-(4-Methyl-Pyridin-2-Yloxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	944390-87-8
Molecular Formula	C16H24N2O3
Molecular Weight	292.38 g/mol
Synonyms	tert-Butyl 4-[(4-methylpyridin-2-yl)oxy]piperidine-1-carboxylate; 1-Boc-4-[(4-methyl-2-pyridyl)oxy]piperidine; 4-(4-Methyl-2-pyridyloxy)piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-[(4-methyl-2-pyridinyl)oxy]piperidine; 4-(4-Methylpyridin-2-yloxy)piperidine-1-carboxylic acid tert-butyl ester; 4-(4-Methyl-2-pyridinyloxy)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 4-(4-Methyl-Pyridin-2-Yloxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our commitment to quality supports your research and development needs with reliable, high-purity materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.