Description

5-Chloro-2-(Piperidin-4-Yloxy)-Pyridine Dihydrochloride is a high-purity organic salt compound, identified by CAS NO 944390-66-3, serving as a critical pharmaceutical intermediate. Its value lies in providing a reliable and consistent building block for complex molecular synthesis, ensuring downstream process integrity. This product is essential for research and development chemists and manufacturers in the pharmaceutical and agrochemical industries, particularly those developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially in central nervous system (CNS) and oncology research.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, leveraging its heterocyclic structure.
• Chemical Synthesis: Serves as a versatile precursor for creating more complex piperidine- and pyridine-containing compounds.
• Academic & Contract Research: Employed in university and CRO laboratories for medicinal chemistry programs and structure-activity relationship (SAR) studies.
• Process Development: Used for scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Custom Synthesis: A starting material for the tailored manufacture of specialty chemicals and fine chemicals for specific client projects.

Basic Information

Product Name	5-Chloro-2-(Piperidin-4-Yloxy)-Pyridine Dihydrochloride
CAS No.	944390-66-3
Molecular Formula	C10H14Cl2N2O
Molecular Weight	265.14 g/mol
Synonyms	5-Chloro-2-[(4-piperidinyl)oxy]pyridine dihydrochloride; 2-(Piperidin-4-yloxy)-5-chloropyridine dihydrochloride; 5-Chloro-2-(piperidin-4-yloxy)pyridine hydrochloride (1:2); 5-Chloro-2-(4-piperidyloxy)pyridine dihydrochloride; 944390-66-3; UNII-8Q5F3Q2Q4K; 8Q5F3Q2Q4K
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-(Piperidin-4-Yloxy)-Pyridine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.