Description

5-Chloro-2-Acetamidopyridine-4-Carboxylic Acid is a high-purity, multi-functional pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both chloro and acetamido substituents, makes it an invaluable intermediate for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its heterocyclic core for bioactivity.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes.
• Advanced Material Development: A building block for organic electronic materials and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and small-scale API batches.

Basic Information

Product Name	5-Chloro-2-Acetamidopyridine-4-Carboxylic Acid
CAS No.	944390-08-3
Molecular Formula	C8H7ClN2O3
Molecular Weight	214.61 g/mol
Synonyms	5-Chloro-2-acetamidopyridine-4-carboxylic acid; 4-Pyridinecarboxylic acid, 5-chloro-2-(acetylamino)-; 2-Acetamido-5-chloropyridine-4-carboxylic acid; 5-Chloro-2-(acetylamino)isonicotinic acid; 5-Chloro-2-acetamidoisonicotinic acid; 5-Chloro-2-(acetylamino)-4-pyridinecarboxylic acid; 944390-08-3; 2-Acetamido-5-chloro-4-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Acetamidopyridine-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.