Description

4,4-Difluorobutanoic Acid is a versatile fluorinated carboxylic acid building block of significant interest in advanced organic synthesis. Its value lies in the strategic incorporation of fluorine atoms, which can dramatically alter the physical, chemical, and biological properties of target molecules. This compound is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing novel active ingredients, as well as by specialty chemical producers for creating advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated active pharmaceutical ingredients (APIs), where fluorine substitution is used to modulate metabolism, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, leveraging fluorine's ability to enhance lipophilicity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated components in electronic display and lighting technologies.
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, imparting valuable properties such as chemical resistance, low surface energy, and thermal stability.
• Organic Synthesis Building Block: Utilized in various carbon-chain elongation and functional group transformation reactions, including nucleophilic substitutions and condensations.
• Fluorine Chemistry Research: An important reagent for academic and industrial research focused on exploring new fluorination methodologies and structure-activity relationships.

Basic Information

Product Name	4,4-Difluorobutanoic Acid
CAS No.	944328-72-7
Molecular Formula	C4H6F2O2
Molecular Weight	124.09 g/mol
Synonyms	4,4-Difluorobutyric Acid; 4,4-Difluorobutanoic Acid; 4,4-Difluorobutanoic acid; Butanoic acid, 4,4-difluoro-; 4,4-Difluoro-butanoic acid; 4,4-Difluoro-butyric acid; 4,4-Difluorobuttersäure (German)
EINECS	Contact for details

Quality Control

Our 4,4-Difluorobutanoic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.