Description

5-Azaspiro[2.4]heptan-7-ol is a specialized heterocyclic building block featuring a unique spirocyclic structure. This compound is of significant interest in advanced organic synthesis and pharmaceutical research, serving as a key intermediate for the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate complex, nitrogen-containing spiro scaffolds into their molecular designs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Ligand Synthesis: Serves as a building block for creating complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Academic & Discovery Chemistry: A valuable scaffold for exploring new chemical space and structure-activity relationships (SAR) in medicinal chemistry programs.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	5-Azaspiro[2.4]heptan-7-ol
CAS No.	944258-72-4
Molecular Formula	C6H11NO
Molecular Weight	113.16 g/mol
Synonyms	7-Hydroxy-5-azaspiro[2.4]heptane; 5-Azaspiro[2.4]heptan-7-ol; 5-Azaspiro[2.4]heptan-7-ol, 9CI; 5-Azaspiro[2.4]heptan-7-ol (9CI); Spiro[cyclopropane-1,2'-pyrrolidin]-5'-ol
EINECS	Contact for details

Quality Control

Our 5-Azaspiro[2.4]heptan-7-ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity building blocks for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.