Description

1H-Pyrrolo[2,3-B]Pyridine-5-Carboxylic Acid, 4-Chloro-2-Methyl- is a high-value heterocyclic building block and key pharmaceutical intermediate. This compound matters for its role in the synthesis of complex molecules, particularly in medicinal chemistry for developing novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries focused on innovation in small molecule drug discovery.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in kinase inhibitor research and other targeted therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing more complex fused ring systems and functionalized pyrrolopyridine derivatives in laboratory settings.
• Material Science Research: Potential application in the development of organic electronic materials due to its conjugated π-system.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.

Basic Information

Item	Details
Product Name	1H-Pyrrolo[2,3-B]Pyridine-5-Carboxylic Acid, 4-Chloro-2-Methyl-
CAS No.	944123-14-2
Molecular Formula	C9H7ClN2O2
Molecular Weight	210.62 g/mol
Synonyms	4-Chloro-2-methyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid; 4-Chloro-2-methyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid; 4-Chloro-2-methyl-7-azaindole-5-carboxylic acid; 4-Chloro-2-methyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid; 944123-14-2; 4-Chloro-2-methyl-7-azaindole-5-carboxylic acid; 4-Chloro-2-methyl-1H-7-azaindole-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-5-Carboxylic Acid, 4-Chloro-2-Methyl- is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), related substances, and other critical parameters is provided with every shipment. We support cGMP compliance for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture uptake. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.