Description

2-[(4-Methoxyphenyl)Dimethylsilyl]Benzyl Alcohol is a specialized organosilicon intermediate featuring a benzyl alcohol moiety protected by a (4-methoxyphenyl)dimethylsilyl group. This compound is valued for its role as a versatile building block in advanced organic synthesis, particularly for introducing silicon-containing functional groups with orthogonal reactivity. It is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures and novel silicone-based polymers.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring silicon-based bioisosteres or protective group strategies.
• Agrochemical Synthesis: Serves as a key precursor in the development of novel pesticides, herbicides, and plant growth regulators with enhanced properties.
• Advanced Material Precursor: Employed in the production of specialty silicones, silicone resins, and hybrid organic-inorganic materials for coatings, electronics, and optics.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Hiyama coupling) due to its organosilicon functionality.
• Polymer Modification: Utilized to functionalize polymers, introducing silyl-protected alcohol groups for subsequent chemical modification or to alter material properties.
• Organic Synthesis Building Block: Provides a protected benzyl alcohol handle for multi-step synthetic sequences in academic and industrial research laboratories.

Basic Information

Item	Detail
Product Name	2-[(4-Methoxyphenyl)Dimethylsilyl]Benzyl Alcohol
CAS No.	944064-51-1
Molecular Formula	C16H20O2Si
Molecular Weight	272.42 g/mol
Synonyms	[2-[(4-Methoxyphenyl)dimethylsilyl]phenyl]methanol; (2-Hydroxymethylphenyl)dimethyl(4-methoxyphenyl)silane; 2-(Hydroxymethyl)-N,N-dimethyl-4-methoxybenzenesilanamine; Benzyl alcohol, 2-[(4-methoxyphenyl)dimethylsilyl]-; Dimethyl(4-methoxyphenyl)[2-(hydroxymethyl)phenyl]silane
EINECS	Contact for details

Quality Control

Our production of 2-[(4-Methoxyphenyl)Dimethylsilyl]Benzyl Alcohol adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP principles and ISO 9001 standards ensures reliable supply for demanding R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.