Description

6-Bromo-8-Methyl-4H-Pyrido[3,2-B][1,4]Oxazin-3-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial building block for the development of new drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of complex molecules.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the life sciences sector.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	6-Bromo-8-Methyl-4H-Pyrido[3,2-B][1,4]Oxazin-3-One
CAS No.	943994-62-5
Molecular Formula	C8H5BrN2O2
Molecular Weight	241.04 g/mol
Synonyms	6-Bromo-8-methyl-4H-pyrido[3,2-b][1,4]oxazin-3-one; 6-Bromo-8-methyl-3H,4H-pyrido[3,2-b][1,4]oxazin-3-one; 943994-62-5; 6-Bromo-8-methyl-4H-pyrido[3,2-b]-1,4-oxazin-3-one; 6-Bromo-8-methyl-4H-[1,4]oxazino[3,2-b]pyridin-3-one; 6-Bromo-8-methyl-3,4-dihydro-1,4-oxazino[3,2-b]pyridin-3-one
EINECS	Contact for details

Quality Control

Our 6-Bromo-8-Methyl-4H-Pyrido[3,2-B][1,4]Oxazin-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.