Description

4-(2-Fluoro-4-Methoxyphenyl)Piperidine is a high-value fluorinated piperidine derivative, a key building block in modern organic synthesis. Its unique structure, featuring both fluorine and methoxy substituents on the aromatic ring, makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and advanced materials. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and development of new therapeutic agents, particularly within medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of complex drug candidates, especially for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Agrochemical Development: Acts as a building block for creating novel pesticides and herbicides, leveraging the bioactivity-enhancing properties of the fluorine atom.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and material science applications.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and target identification.

Basic Information

Product Name	4-(2-Fluoro-4-Methoxyphenyl)Piperidine
CAS No.	943917-19-9
Molecular Formula	C12H16FNO
Molecular Weight	209.26 g/mol
Synonyms	4-(2-Fluoro-4-methoxyphenyl)piperidine; 2-Fluoro-4-(4-piperidyl)anisole; 1-(2-Fluoro-4-methoxyphenyl)piperidine; 4-(2-Fluoro-4-methoxyphenyl)piperidine hydrochloride (salt form); Piperidine, 4-(2-fluoro-4-methoxyphenyl)-; FMPP (abbreviation); 2-Fluoro-4-piperidin-4-ylanisole
EINECS	Contact for details

Quality Control

Every batch of 4-(2-Fluoro-4-Methoxyphenyl)Piperidine is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are developed to meet the stringent requirements of research and pre-clinical development. A detailed Certificate of Analysis (COA) providing results for purity, related substances, and other critical parameters is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorinating agents. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.