Description

tert-Butyl 2-Methoxypyridin-4-Ylmethylcarbamate is a high-purity, protected amine derivative used as a critical building block in advanced organic synthesis. This compound matters because it provides a versatile and reactive handle for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), fine chemicals, and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of novel drug candidates, particularly those targeting the central nervous system or as kinase inhibitors.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the pyridine moiety for biological activity.
• Peptide Mimetics & Conjugation: The carbamate-protected amine group serves as a precursor for introducing functionalized amine linkages into larger molecular architectures.
• Ligand Synthesis for Catalysis: Employed in the preparation of specialized nitrogen-containing ligands for metal-catalyzed reactions.
• Chemical Biology Probes: Useful for creating tagged or modified small molecules for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific projects requiring this precise chemical scaffold.

Basic Information

Product Name	tert-Butyl 2-Methoxypyridin-4-Ylmethylcarbamate
CAS No.	943845-48-5
Molecular Formula	C12H18N2O3
Molecular Weight	238.28 g/mol
Synonyms	tert-Butyl N-[(2-Methoxy-4-pyridinyl)methyl]carbamate; 4-[[(tert-Butoxycarbonyl)amino]methyl]-2-methoxypyridine; 2-Methoxy-4-pyridinemethanamine, N-BOC-protected; BOC-2-Methoxy-4-pyridylmethylamine; N-Boc-2-methoxy-4-aminomethylpyridine; tert-Butyl (2-methoxypyridin-4-yl)methylcarbamate; 4-(Boc-aminomethyl)-2-methoxypyridine
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Methoxypyridin-4-Ylmethylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with complete batch data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.