Description

2-Pyridinecarboxylic Acid, 5-Formyl-, 1,1-Dimethylethyl Ester is a high-purity, functionalized pyridine derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a formyl group and a protected carboxylic acid, makes it an exceptionally versatile intermediate for constructing complex heterocyclic frameworks. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand Synthesis: Serves as a starting material for creating sophisticated chelating ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and cellular processes.
• Advanced Material Development: A building block for novel polymers and organic electronic materials requiring specific pyridine-based architectures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2-Pyridinecarboxylic Acid, 5-Formyl-, 1,1-Dimethylethyl Ester
CAS No.	943844-15-3
Molecular Formula	C12H15NO3
Molecular Weight	221.25 g/mol
Synonyms	5-Formylpicolinic Acid tert-Butyl Ester; tert-Butyl 5-Formylpicolinate; 5-Formyl-2-pyridinecarboxylic Acid 1,1-Dimethylethyl Ester; 2-Pyridinecarboxylic Acid, 5-Formyl-, tert-Butyl Ester; Picolinic Acid, 5-Formyl-, tert-Butyl Ester; tert-Butyl 5-Formyl-2-pyridinecarboxylate; 5-Formylpicolinic Acid t-Butyl Ester
EINECS	Contact for details

Quality Control

Every batch of 2-Pyridinecarboxylic Acid, 5-Formyl-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.