Description

3-Bromo-5-Fluoropyridine is a high-purity halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its dual functionalization, offering precise reactivity for constructing complex molecular architectures. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers, liquid crystals, and electronic materials.
• Cross-Coupling Reactions: An essential substrate for Suzuki, Stille, and Negishi cross-coupling reactions to form biaryl and heterobiaryl structures.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development and exploring new synthetic pathways.
• Ligand and Catalyst Design: Used to synthesize novel nitrogen-containing ligands for transition metal catalysis.

Basic Information

Product Name	3-Bromo-5-Fluoropyridine
CAS No.	943778-91-4
Molecular Formula	C5H3BrFN
Molecular Weight	175.99 g/mol
Synonyms	5-Fluoro-3-bromopyridine; 3-Bromo-5-fluoropyridine; 5-Bromo-3-fluoropyridine; Pyridine, 3-bromo-5-fluoro-; 3-Br-5-F-Pyridine; 3-Bromo-5-fluoro-pyridine; 3-Br-5-F-Py
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Fluoropyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates for regulated R&D and production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.