Description

5-Methyl-4,5-Dihydro-3H,3'H-Spiro[Furan-2,1'-Isobenzofuran] is a high-value, complex spirocyclic compound with the CAS registry number 943643-08-1. This specialty chemical serves as a critical advanced intermediate for synthesizing complex molecules in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working in fine chemical synthesis. Its unique fused spiro structure makes it a valuable building block for creating novel compounds with specific biological activities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, leveraging its complex heterocyclic framework.
• Material Science Precursor: Potential monomer or precursor for developing specialty polymers with unique optical or electronic properties.
• Organic Synthesis & Catalysis: Valuable scaffold in methodological chemistry for studying new spirocyclization and ring-forming reactions.
• Ligand & Catalyst Development: The oxygen-rich heterocyclic structure can be functionalized to create novel ligands for asymmetric catalysis.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and research in fine chemical manufacturing.

Basic Information

Product Name	5-Methyl-4,5-Dihydro-3H,3'H-Spiro[Furan-2,1'-Isobenzofuran]
CAS No.	943643-08-1
Molecular Formula	C13H14O2
Molecular Weight	202.25 g/mol
Synonyms	5-Methyl-4,5-dihydro-3H-spiro[2-benzofuran-1,2'-oxolane]; 5-Methyldihydrospiro[isobenzofuran-1(3H),2'-oxolane]; Spiro[isobenzofuran-1(3H),2'-oxolane], 5-methyl-4,5-dihydro-; 943643-08-1; 5-Methyl-4,5-dihydrospiro[isobenzofuran-1(3H),2'-oxolane]; Spirocyclic furan-isobenzofuran derivative
EINECS	Contact for details

Quality Control

Our 5-Methyl-4,5-Dihydro-3H,3'H-Spiro[Furan-2,1'-Isobenzofuran] is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.