Description

4-[Isocyano-(Toluene-4-Sulfonyl)-Methyl]-1,2-Dimethoxy-Benzene is a specialized organic building block featuring a reactive isocyano group and a tosyl-protected methylene unit. This compound is valued for its role as a versatile intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for constructing heterocyclic compounds and complex scaffolds in drug discovery programs.
• Agrochemical Research: Used in the synthesis of novel pesticides and herbicides, leveraging its reactive functional groups.
• Chemical Biology Probe Development: Serves as a precursor for isocyanide-based multicomponent reactions (e.g., Ugi, Passerini) to create diverse compound libraries.
• Material Science Research: Potential building block for the synthesis of functional polymers and advanced organic materials.
• Academic & Contract Research: Employed in methodological studies and as a reagent for developing new synthetic pathways in organic chemistry.

Basic Information

Product Name	4-[Isocyano-(Toluene-4-Sulfonyl)-Methyl]-1,2-Dimethoxy-Benzene
CAS No.	943614-50-4
Molecular Formula	C₁₇H₁₇NO₄S
Molecular Weight	331.39 g/mol
Synonyms	1,2-Dimethoxy-4-[(isocyanomethyl)sulfonyl]benzene; 4-(Isocyanomethylsulfonyl)-1,2-dimethoxybenzene; 4-[(Isocyanomethyl)sulfonyl]-1,2-dimethoxybenzene; 4-[(Isocyanomethyl)sulfonyl]veratrole; TosMIC Veratrole Derivative; 4-[Isocyano-(p-Tolylsulfonyl)-Methyl]-1,2-Dimethoxy-Benzene; 1,2-Dimethoxy-4-[(p-tolylsulfonyl)(isocyano)methyl]benzene
EINECS	Contact for details

Quality Control

Our 4-[Isocyano-(Toluene-4-Sulfonyl)-Methyl]-1,2-Dimethoxy-Benzene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.