Description

4-Fluorophenyl Isocyanate is a versatile and highly reactive aromatic isocyanate building block, essential for synthesizing advanced chemical intermediates. Its primary value lies in introducing the fluorophenyl carbamate or urea moiety, which can significantly alter the physical, chemical, and biological properties of target molecules. This compound is critically needed by R&D and production chemists in the pharmaceutical, agrochemical, and specialty polymer industries for developing new active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediates: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), including potential enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the fluorine atom enhances bioavailability and metabolic stability.
• Polymer Science: Serves as a monomer or cross-linking agent in the production of specialty polyurethanes, polyureas, and coatings with tailored properties like chemical resistance.
• Chemical Research: A fundamental reagent for constructing diverse heterocycles and complex organic molecules via reactions with amines and alcohols.
• Material Science: Employed in surface modification and the development of advanced functional materials, such as liquid crystals and organic semiconductors.

Basic Information

Product Name	4-Fluorophenyl Isocyanate
CAS No.	1195-45-5
Molecular Formula	C7H4FNO
Molecular Weight	137.11 g/mol
Synonyms	p-Fluorophenyl Isocyanate; 1-Fluoro-4-isocyanatobenzene; 4-Fluoro-1-isocyanatobenzene; Isocyanic Acid, 4-Fluorophenyl Ester; 4-Fluorobenzene Isocyanate; FPI; 4-Fluorophenylcarbimide
EINECS	214-806-8

Quality Control

Our 4-Fluorophenyl Isocyanate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at temperatures between 2°C and 8°C (refrigerated) to minimize volatility and degradation. Due to its highly volatile and hygroscopic (moisture-sensitive) nature, containers should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) and allowed to equilibrate to room temperature before opening to prevent moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.