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4-Chlorophenyl Isocyanate CAS NO 104-12-1
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CAS No.:104-12-1
Grade:Pharmacy Grade
Content:99.0%
Brand:Customizable
Packaging:Customizable
Description
4-Chlorophenyl Isocyanate is a versatile and reactive aromatic isocyanate building block essential for synthesizing advanced chemical intermediates. Its primary value lies in introducing the 4-chlorophenyl carbamoyl moiety, enabling the creation of compounds with tailored properties for high-performance applications. This product is critically needed by R&D laboratories and industrial manufacturers in the agrochemical, pharmaceutical, and specialty polymer sectors for developing active ingredients, pharmaceutical scaffolds, and functional materials.
Application
- Agrochemical Intermediate: Key precursor in the synthesis of phenylurea herbicides and other crop protection agents.
- Pharmaceutical Synthesis: Building block for creating potential drug candidates, including enzyme inhibitors and receptor ligands.
- Polymer Modification: Used to produce polyurethanes and polyurea coatings with enhanced chemical resistance and durability.
- Crosslinking Agent: Imparts crosslinks in specialty resins and elastomers to improve thermal and mechanical properties.
- Chemical Research (R&D): Fundamental reagent for exploring new carbamate and urea derivatives in academic and industrial research.
- Dye and Pigment Manufacturing: Intermediate in the production of certain specialized colorants and photographic chemicals.
Basic Information
| Product Name | 4-Chlorophenyl Isocyanate |
| CAS No. | 104-12-1 |
| Molecular Formula | C7H4ClNO |
| Molecular Weight | 153.56 g/mol |
| Synonyms | p-Chlorophenyl isocyanate; 1-Chloro-4-isocyanatobenzene; 4-Chlorophenylcarbonyl imide; Isocyanic acid, 4-chlorophenyl ester; PCI; 4-CPI; NSC 406925 |
| EINECS | 203-176-6 |
Quality Control
Our 4-Chlorophenyl Isocyanate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including assay by titration and impurity profile analysis by GC/HPLC, to ensure high purity and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request, supporting compliance with global regulatory and research standards.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 15-25°C. Due to its highly volatile and moisture-sensitive nature, containers must be kept tightly sealed under a dry inert atmosphere (e.g., nitrogen) to prevent hydrolysis and polymerization. Keep away from strong bases, alcohols, amines, and sources of ignition.
Specification
| Item | Specification |
|---|---|
| Appearance | Clear, colorless to pale yellow liquid |
| Identification (IR) | Conforms |
| Assay (GC/Titration) | ≥ 98.0% |
| Color (APHA) | ≤ 50 |
| Density at 20°C | ~1.25 g/cm³ |
| Water Content (KF) | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Rigorous Quality Assurance
Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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Our in-house lab drives process innovation, new product development, and tailored synthesis solutions.





