Description

Ethyl Isocyanoacetate is a versatile organic building block characterized by its reactive isocyano and ester functional groups. This compound is essential for the synthesis of complex heterocyclic structures, including oxazoles and imidazoles, which are core scaffolds in numerous active pharmaceutical ingredients. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of heterocyclic compounds such as oxazoles and imidazoles, which are prevalent in drug discovery and development.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its ability to form complex molecular architectures.
• Peptide Mimetics & Bioconjugation: Employed in the creation of peptide analogs and for bioconjugation chemistry due to the reactivity of the isocyano group.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of novel polymers and functional materials.
• Catalyst & Ligand Preparation: Utilized in the synthesis of specialized ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Acts as a building block for creating activity-based probes and other tools for studying biological systems.

Basic Information

Product Name	Ethyl Isocyanoacetate
CAS No.	2999-46-4
Molecular Formula	C5H7NO2
Molecular Weight	113.11 g/mol
Synonyms	Ethyl 2-isocyanoacetate; Isocyanoacetic Acid Ethyl Ester; NSC 401119; Ethyl (isocyanato)acetate; Acetic acid, isocyano-, ethyl ester
EINECS	221-076-8

Quality Control

Our Ethyl Isocyanoacetate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.