Description

1H-Pyrrolo[2,3-B]Pyridin-3-Amine, 4-Bromo- is a high-purity, advanced pharmaceutical intermediate with a distinct fused heterocyclic structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in oncology and kinase inhibitor research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule drugs, especially kinase inhibitors and targeted cancer therapies.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Used in the construction of complex fused heterocyclic systems due to its reactive amine and halogen functional groups.
• Biochemical Research: Employed in the development of chemical probes and tool compounds for studying biological pathways and enzyme functions.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridin-3-Amine, 4-Bromo-
CAS No.	943323-65-7
Molecular Formula	C7H6BrN3
Molecular Weight	212.05 g/mol
Synonyms	4-Bromo-1H-pyrrolo[2,3-b]pyridin-3-amine; 4-Bromo-3-amino-7-azaindole; 4-Bromo-7-azaindol-3-ylamine; 4-Bromo-1H-pyrrolo[2,3-b]pyridin-3-amine; 4-Bromo-7-aza-3-indolamine; 4-Bromo-3-amino-1H-pyrrolo[2,3-b]pyridine; 4-Bromo-7-azaindol-3-amine
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridin-3-Amine, 4-Bromo- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.