Description

1H-Pyrrolo[2,3-B]Pyridine, 4-Bromo-3-Phenyl-1-(Phenylsulfonyl)- is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound matters because it provides a versatile and reactive scaffold for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for lead optimization and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its unique fused-ring structure.
• Material Science: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology: Employed as a molecular probe or tag in bioconjugation and proteomics research due to its reactive bromo and sulfonyl groups.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized compounds for clients.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 4-Bromo-3-Phenyl-1-(Phenylsulfonyl)-
CAS No.	943322-46-1
Molecular Formula	C19H13BrN2O2S
Molecular Weight	413.29 g/mol
Synonyms	4-Bromo-3-phenyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1-(Benzenesulfonyl)-4-bromo-3-phenyl-1H-pyrrolo[2,3-b]pyridine; 4-Bromo-3-phenyl-1-tosyl-1H-pyrrolo[2,3-b]pyridine (common alias); 943322-46-1; 1H-Pyrrolo[2,3-b]pyridine, 4-bromo-3-phenyl-1-(phenylsulfonyl)-; 4-Bromo-3-phenyl-1H-pyrrolo[2,3-b]pyridine 1-sulfonate
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine, 4-Bromo-3-Phenyl-1-(Phenylsulfonyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.