Description

n-(3-Ethynylimidazo[1,2-A]Pyridin-8-Yl)-Acetamide is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure incorporating an ethynyl functional group. This compound is of significant value for research and development in medicinal chemistry, particularly in the synthesis of novel bioactive molecules. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, especially within oncology and CNS drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its imidazopyridine core and reactive ethynyl handle.
• Kinase Inhibitor Development: Serves as a precursor in the creation of potential kinase inhibitors, a major class of therapeutics in oncology.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying biological processes and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic projects.
• Academic Research: Used in university and institutional labs for exploratory research in heterocyclic chemistry and drug discovery.

Basic Information

Product Name	n-(3-Ethynylimidazo[1,2-A]Pyridin-8-Yl)-Acetamide
CAS No.	943320-54-5
Molecular Formula	C11H9N3O
Molecular Weight	199.21 g/mol
Synonyms	N-(3-Ethynylimidazo[1,2-a]pyridin-8-yl)acetamide; 8-Acetamido-3-ethynylimidazo[1,2-a]pyridine; Acetamide, N-[3-ethynylimidazo[1,2-a]pyridin-8-yl]-; 943320-54-5; 3-Ethynyl-8-acetamidoimidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine-8-acetamide, 3-ethynyl-; N-(3-Ethynylimidazo[1,2-a]pyridin-8-yl)ethanamide
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, residual solvents, and related substances are available upon request. We adhere to strict internal quality management protocols to support our customers' R&D and cGMP manufacturing needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.