Description

6-[(1-Hydroxy-1,3-Dihydro-2,1-Benzoxaborol-5-Yl)Oxy]Nicotinonitrile is a sophisticated heterocyclic compound featuring a benzoxaborole core linked to a cyanopyridine moiety, representing a key intermediate in modern pharmaceutical and agrochemical research. This compound matters due to its unique structural framework, which is highly valuable for the development of novel enzyme inhibitors and active pharmaceutical ingredients (APIs). It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for synthesizing targeted bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel boron-containing drug candidates, particularly protease inhibitors and anti-infective agents.
• Agrochemical Research: Used in developing new generations of herbicides and fungicides that leverage the bioactivity of the benzoxaborole scaffold.
• Chemical Biology Probe: Serves as a precursor for creating molecular probes to study enzyme function and biological pathways.
• Material Science: Potential intermediate in the synthesis of organic electronic materials and metal-organic frameworks (MOFs) due to its rigid, conjugated structure.
• Academic & Institutional R&D: Employed in universities and research institutes for fundamental studies in medicinal chemistry and heterocyclic compound synthesis.

Basic Information

Product Name	6-[(1-Hydroxy-1,3-Dihydro-2,1-Benzoxaborol-5-Yl)Oxy]Nicotinonitrile
CAS No.	943311-33-9
Molecular Formula	C13H9BN2O3
Molecular Weight	252.04 g/mol
Synonyms	5-((6-Cyanopyridin-3-yl)oxy)-2,1-benzoxaborol-1(3H)-ol; 6-[(1-Hydroxy-3H-2,1-benzoxaborol-5-yl)oxy]nicotinonitrile; 6-[(1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yl)oxy]nicotinonitrile; 6-(1-Hydroxy-1,3-dihydro-2,1-benzoxaborol-5-yloxy)nicotinonitrile; Benzoxaborole-nicotinonitrile derivative; CAS 943311-33-9
EINECS	Contact for details

Quality Control

Our 6-[(1-Hydroxy-1,3-Dihydro-2,1-Benzoxaborol-5-Yl)Oxy]Nicotinonitrile is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.