Description

Cy7 CAS NO 943298-08-6 is a near-infrared (NIR) cyanine dye belonging to the heptamethine indocyanine family. This compound is a critical reagent for advanced fluorescence labeling and detection due to its deep tissue penetration and minimal background interference. It is essential for researchers and manufacturers in the fields of bioconjugation, bioimaging, and in vivo diagnostics, providing a reliable tool for sensitive and specific detection.

Application

• Fluorescent Labeling of Biomolecules: Conjugation to antibodies, peptides, nucleic acids, and proteins for detection assays.
• In Vivo and In Vitro Imaging: Used as a contrast agent for deep-tissue fluorescence imaging in preclinical research.
• Flow Cytometry and Cell Sorting: Staining of cells for analysis and isolation based on specific markers.
• Optical Sensor Development: Integration into sensor platforms for detecting pH, ions, or specific analytes.
• Polymer and Material Science: Incorporation into nanoparticles, polymers, or coatings to impart NIR fluorescence properties.
• Diagnostic Kit Manufacturing: A key component in the production of lateral flow assays and other diagnostic devices.

Basic Information

Product Name	Cy7
CAS No.	943298-08-6
Molecular Formula	C37H45ClN2O6S2
Molecular Weight	713.37 g/mol
Synonyms	Cy7 dye; Cyanine7; 2-[7-[1,3-Dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-1H-benz[e]indolium hydroxide, inner salt; Sulfo-Cyanine7; 1H-Benz[e]indolium, 2-[7-(1,1-dimethyl-1,3-dihydro-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene)-1,3,5-heptatrien-1-yl]-1,1-dimethyl-3-(4-sulfobutyl)-, inner salt; NIR dye Cy7; Heptamethine cyanine dye
EINECS	Contact for details

Quality Control

Our Cy7 dye is manufactured under strict quality management systems to ensure batch-to-batch consistency and high performance. Each lot undergoes comprehensive analytical testing, including HPLC for purity, spectrophotometry for absorbance/emission verification, and functional testing in conjugation assays. Certificates of Analysis (COA) with detailed spectral data are provided to guarantee the product meets the stringent requirements for research and diagnostic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, desiccate at -20°C under inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Dark green to blue-green powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Absorption Maximum (λmax)	747 - 753 nm
Emission Maximum (λem)	770 - 780 nm
Extinction Coefficient (ε)	≥ 200,000 L·mol⁻¹·cm⁻¹
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in water, DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.