Description

8-Bromo-3,7-Difluoro-2-Methoxy-1,5-Naphthyridine is a high-purity, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound is critical for researchers and manufacturers requiring precise molecular architecture in the development of novel active ingredients. It is primarily utilized in the pharmaceutical and agrochemical sectors as a key intermediate for creating complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Serves as a key precursor in the design and synthesis of new-generation herbicides, fungicides, and insecticides, leveraging its unique halogenated naphthyridine structure.
• Material Science: Used in the research and development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient aromatic system.
• Chemical Synthesis: Functions as a versatile scaffold for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to create diverse chemical libraries for screening.
• Life Science Reagents: Employed in the synthesis of fluorescent probes, biomarkers, and other diagnostic tools that require specific photophysical properties.

Basic Information

Product Name	8-Bromo-3,7-Difluoro-2-Methoxy-1,5-Naphthyridine
CAS No.	943025-91-0
Molecular Formula	C9H5BrF2N2O
Molecular Weight	287.05 g/mol
Synonyms	8-Bromo-3,7-difluoro-2-methoxy-1,5-naphthyridine; 1,5-Naphthyridine, 8-bromo-3,7-difluoro-2-methoxy-; 943025-91-0; 8-Br-3,7-F2-2-MeO-1,5-Naphthyridine; 2-Methoxy-8-bromo-3,7-difluoro-1,5-naphthyridine
EINECS	Contact for details

Quality Control

Our 8-Bromo-3,7-Difluoro-2-Methoxy-1,5-Naphthyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.