Description

(2-Chloro-5-Fluoro-6-Methoxy-Pyridin-3-Yl)-Carbamic Acid tert-Butyl Ester is a high-purity, multi-functional pyridine derivative designed for advanced chemical synthesis. This compound serves as a critical protected intermediate, enabling the precise construction of complex molecules in regulated industries. It is primarily required by pharmaceutical and agrochemical research & development teams for the development of new active ingredients, where its specific halogen and methoxy substitution pattern offers valuable synthetic handles.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.
• Material Science Precursor: Potential intermediate in the development of specialty chemicals, ligands for catalysis, or advanced organic materials.

Basic Information

Product Name	(2-Chloro-5-Fluoro-6-Methoxy-Pyridin-3-Yl)-Carbamic Acid tert-Butyl Ester
CAS No.	943025-87-4
Molecular Formula	C11H14ClFN2O3
Molecular Weight	276.69 g/mol
Synonyms	tert-Butyl N-(2-chloro-5-fluoro-6-methoxy-3-pyridinyl)carbamate; Carbamic acid, N-(2-chloro-5-fluoro-6-methoxy-3-pyridinyl)-, 1,1-dimethylethyl ester; 2-Chloro-5-fluoro-6-methoxypyridin-3-amine, N-Boc protected; Boc-2-Chloro-5-fluoro-6-methoxypyridin-3-amine; 3-((tert-Butoxycarbonyl)amino)-2-chloro-5-fluoro-6-methoxypyridine; N-Boc-3-amino-2-chloro-5-fluoro-6-methoxypyridine; 943025-87-4; BOC-Protected 2-Chloro-5-Fluoro-6-Methoxy-3-Aminopyridine
EINECS	Contact for details

Quality Control

Every batch of (2-Chloro-5-Fluoro-6-Methoxy-Pyridin-3-Yl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We support development needs with custom purity grades, including research and GMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Any single unknown impurity	≤1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.