Description

2-Chloro-5-Fluoro-6-(Methyloxy)-3-Pyridinecarboxylic Acid is a high-purity, multi-functional pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique halogenated and methoxylated structure makes it an invaluable intermediate for constructing complex molecules with tailored properties. This compound is essential for R&D and production chemists in the pharmaceutical and agrochemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where its halogenated pyridine core contributes to biological activity.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and functional polymers.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Chloro-5-Fluoro-6-(Methyloxy)-3-Pyridinecarboxylic Acid
CAS No.	943025-86-3
Molecular Formula	C8H5ClFNO3
Molecular Weight	217.58 g/mol
Synonyms	2-Chloro-5-fluoro-6-methoxynicotinic acid; 6-Methoxy-2-chloro-5-fluoronicotinic acid; 3-Pyridinecarboxylic acid, 2-chloro-5-fluoro-6-methoxy-; 2-Chloro-5-fluoro-6-methoxy-pyridine-3-carboxylic acid; 943025-86-3; 2-Chloro-5-fluoro-6-methoxynicotinic acid; 6-Methoxy-2-chloro-5-fluoropyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Fluoro-6-(Methyloxy)-3-Pyridinecarboxylic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.