Description

1-(5-(Trifluoromethyl)Pyridin-2-Yl)Ethanamine is a high-value pyridine derivative featuring a trifluoromethyl substituent, a structural motif prized for its ability to modulate the physicochemical properties of advanced molecules. This compound serves as a critical pharmaceutical intermediate and agrochemical building block, enabling the synthesis of novel active ingredients with enhanced metabolic stability and bioavailability. It is essential for R&D and production teams in the life sciences and specialty chemical sectors seeking to develop next-generation therapeutics and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental persistence.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for biochemical and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up production under cGMP or ISO standards.

Basic Information

Item	Details
Product Name	1-(5-(Trifluoromethyl)Pyridin-2-Yl)Ethanamine
CAS No.	942938-59-2
Molecular Formula	C8H9F3N2
Molecular Weight	190.17 g/mol
Synonyms	1-[5-(Trifluoromethyl)pyridin-2-yl]ethanamine; 1-[5-(Trifluoromethyl)-2-pyridinyl]ethanamine; 2-(1-Aminoethyl)-5-(trifluoromethyl)pyridine; α-Methyl-5-(trifluoromethyl)-2-pyridinemethanamine; N-(5-Trifluoromethylpyrid-2-yl)ethylamine; 5-(Trifluoromethyl)-2-pyridineethanamine, α-methyl-; (5-(Trifluoromethyl)pyridin-2-yl)ethanamine
EINECS	Contact for details

Quality Control

Our 1-(5-(Trifluoromethyl)Pyridin-2-Yl)Ethanamine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and batch-to-batch consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting identity, purity, and impurity profiles. Production can be aligned with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.